Research Paper Volume 16, Issue 10 pp 9216—9227

The protective effects of Chromofungin in oligomeric amyloid β42 (Aβ42)-induced toxicity in neurons in Alzheimer’s disease

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Figure 5. Chromofungin ameliorated oligomeric Aβ42-induced oxidative stress in M17 neuronal cells. Cells were stimulated with oligomeric Aβ42 (5 μM) with or without Chromofungin (0.5, 1 mM) for 24 hours. (A) Intracellular ROS was measured using DCFH-DA staining; (B) The levels of SOD (n = 6, **P < 0.01 vs. vehicle group; †, ††P < 0.05, 0.01 vs. Aβ42 group).