Research Paper Volume 16, Issue 10 pp 9204—9215

DKK2 promotes the progression of oral squamous cell carcinoma through the PI3K/AKT signaling pathway

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Figure 3. Knockdown of DKK2 can reduce the progression of oral squamous cell carcinoma. (A) Reverse transcription-quantitative polymerase chain reaction was used to verify the knockdown efficiency of CAL27 cell line. (B) Western blot was used to detect the knockdown efficiency of CAL27 cell line. (C) After knockdown of DKK2, EdU assay was used to detect the proliferation of transfected CAL27 cell line. (D) After knockdown of DKK2, scratch assay was used to detect the migration of cells. (E) After knockdown of DKK2, Transwell assay was used to detect the invasion of cells. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001.