Research Paper Volume 16, Issue 10 pp 9072—9105

Sensitivity of substrate translocation in chaperone-mediated autophagy to Alzheimer’s disease progression

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Figure 2. PPI network map of genes contained in S6, was constructed based on STRING database and visualized by Cytoscape. The ranking was performed after filtering by the betweenness centrality algorithm, with nodes closer to the center or colored closer to red indicating higher scores. The results show that GFAP still dominates in this network, and other genes associated with CMA are close to the center of the network.