Research Paper Volume 16, Issue 10 pp 9047—9071

Targeting PRKDC activates the efficacy of antitumor immunity while sensitizing to chemotherapy and targeted therapy in liver hepatocellular carcinoma

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Figure 8. PRKDC knockdown induced cell death, EMT, and halted the cell cycle in LIHC. (A, B) Relative cell death percentages in Huh-7 or Hep-3B cells using trypan blue staining. (C, D) Protein level of apoptosis related markers in Huh-7 or Hep-3B cells. (E, F) Protein level of EMT related markers in Huh-7 or Hep-3B cells. (GJ) Cell cycle analysis between PRKDC knockdown and negative control groups in Huh-7 or Hep-3B cells using flow cytometry.