Research Paper Volume 16, Issue 10 pp 9047—9071
Targeting PRKDC activates the efficacy of antitumor immunity while sensitizing to chemotherapy and targeted therapy in liver hepatocellular carcinoma
Figure 4. Evaluation of exogenous datasets to assess the accuracy and independence of PCDI. (A–C) Kaplan-Meier analysis of overall survival rates in high- and low-PCDI groups, indicating superior prognoses for patients with low PCDI scores compared to those with high PCDI scores. Additionally, the distribution of PCDI based on survival status and time is demonstrated in the three datasets (TCGA, GSE14520, and GSE144269). (D–F) Time-dependent ROC curve analysis of TCGA, GSE14520, and GSE144269 datasets. (G) Univariate Cox regression analysis revealing a significant correlation between PCDI and prognosis. (H) Multivariate Cox regression analysis confirming that PCDI can serve as an independent prognostic factor.