Research Paper Volume 16, Issue 10 pp 9047—9071

Targeting PRKDC activates the efficacy of antitumor immunity while sensitizing to chemotherapy and targeted therapy in liver hepatocellular carcinoma

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Figure 3. Development of a reliable programmed cell death index (PCDI). (A) A comparison of the AUC values for various models and the AUC of the final PCDI is presented. (B) Box plots demonstrate the correlation between PCDI and clinical features such as Grade, Stage, and T. (C) Heatmap displays the expression of PCD genes in the model. (D) Venn diagram illustrates the overlap of enriched hallmark pathways in three datasets (TCAG, GSE144269, and GSE76427). (E) Correlation analysis of genes within the HALLMARK_MYC_TARGETS_V1 pathway.