Research Paper Volume 16, Issue 10 pp 8822—8842

Inflammation-based lung adenocarcinoma molecular subtype identification and construction of an inflammation-related signature with bulk and single-cell RNA-seq data

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Figure 9. Promotion of tumor cell proliferation by RELA. (A, B) Differential expression of RELA in tumor vs. normal tissues, with pronounced upregulation in tumor samples. (C) Microscopic images highlighting cell migration differences across treatments over time. (D) Varying clonogenic potential among treatments, notably between RELA-OE and RELA-Si. (E) Results of the CCK-8 assay presenting enhanced proliferation in the RELA-OE group. (F) In vivo tumor size differences, with RELA-OE tumors being significantly larger.