Research Paper Volume 16, Issue 10 pp 8822—8842
Inflammation-based lung adenocarcinoma molecular subtype identification and construction of an inflammation-related signature with bulk and single-cell RNA-seq data
Figure 1. Identification of two inflammation subtypes in LUAD. (A) Volcano plot of prognosis-related inflammation genes identified by univariate Cox regression analysis. (B) Consensus clustering matrix for k = 2. (C) Consensus of the items (k = 2–4) in each cluster. (D) Violin plots indicating the differences between the 2 subtypes. (E) Heatmap of 49 inflammation response gene expression in different subgroups; red represents high and blue represents low expression levels. (F) Principal component analysis plots. ****P < 0.0001.