Prediction of prognosis and immunotherapy efficacy based on metabolic landscape in lung adenocarcinoma by bulk, single-cell RNA sequencing and Mendelian randomization analyses

Yong Liu; Xiangwei Zhang; Zhaofei Pang; Yadong Wang; Haotian Zheng; Guanghui Wang; Kai Wang; Jiajun Du

doi:doi:10.18632/aging.205838

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Research Paper Volume 16, Issue 10 pp 8772—8809

Prediction of prognosis and immunotherapy efficacy based on metabolic landscape in lung adenocarcinoma by bulk, single-cell RNA sequencing and Mendelian randomization analyses

Figure 4. Evaluation of MPPS model. (A) The 1-, 3-, 5-year receiver operating characteristic (ROC) curves of MPPS model in TCGA-LUAD cohort and GEO validation cohorts. (B) The 1-, 3-, 5-year area under curves (AUC) of MPPS model and 51 published prognostic models of LUAD. (C) C-index of MPPS model and 51 published prognostic models of LUAD.