Research Paper Volume 16, Issue 10 pp 8772—8809
Prediction of prognosis and immunotherapy efficacy based on metabolic landscape in lung adenocarcinoma by bulk, single-cell RNA sequencing and Mendelian randomization analyses
Figure 12. Expression, function, prognosis analyses of MPPS-related gene signature. (A) Correlation of MPPS and gene risk score by LASSO and survival-SVM. (B) The differences of the expression of 7 genes between TCGA-LUAD and normal samples. (C) The differences of the expression of 7 genes between the high- and low-MPPS groups. (D) The correlation of 7 genes expression and metabolic pathways. (E) The correlation of 7 genes expression and 14 biological processes by cancerSEA website. (F) The copy number variation frequency and location in chromosomes of the 7 genes. (G) The Kaplan-Meier analysis of the high- and low-expression of the 7 genes.