Research Paper Volume 16, Issue 10 pp 8645—8656

Mangiferin attenuates lipopolysaccharide-induced neuronal injuries in primary cultured hippocampal neurons

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Figure 7. Mangiferin mediates an anti-apoptotic effect in LPS-exposed cells. (AD) The plots show the flow cytometry of different treatments, and the apoptosis rates are analyzed (E). In the plots, quadrant Q4 shows surviving cells, Q2 and Q3 show dead cells, and Q1 shows cell debris; Q2 and Q3 are used to assess apoptosis. The apoptosis rates in the control, LPS, 20 μmol/L mangiferin with LPS, 40 μmol/L mangiferin with LPS are 2.87%, 26.8%, 14.39%, and 7.02% respectively, all ***P < 0.001.