Research Paper Volume 16, Issue 9 pp 8279—8305
Cancer-associated fibroblast-derived gene signature discriminates distinct prognoses by integrated single-cell and bulk RNA-seq analyses in breast cancer
Figure 7. scRNA-seq analysis of the tumor immune microenvironment features between high/low-risk group. (A) UMAP plot showing the major cell subpopulations of high- and low-risk breast tumors. (B) Relative proportions of diverse cell types across high/low-risk tumors. (C) UMAP plot showing the diverse subsets of myeloid cells in breast cancers. (D) Bubble heatmap showing expression levels of selected signature genes for myeloid cells in breast cancers. Dot size indicates fraction of expressing cells, colored based on normalized expression levels. (E) Relative proportions of diverse subpopulations of myeloid cells across high/low-risk tumors.