Research Paper Volume 16, Issue 9 pp 8260—8278
HLA-B and TIMP1 as hub genes of the ventricular remodeling caused by hypertension
Figure 4. Significant modules and hub genes identified from the PPI network. (A) The first module consists of MS4A4A, HCK, HK3, DOK2, RGS19, PKM, CAPNS1, and GNB2. (B) The second module consists of FLNA, RHOG, MYL6, and ZYX. (C) The first network of hub genes identified by MCC. (D) The second network of hub genes identified by MNC. (E) The third network of hub genes identified by Degree. (F) The fourth network of hub genes identified by EPC. (G) The Venn diagram comprises the common hub genes (HLA-B, CTSL, RHOG, FLNA, MYD88, CAPNS1, and TIMP1).