Research Paper Volume 16, Issue 9 pp 7535—7552
Caloric restriction mitigates age-associated senescence characteristics in subcutaneous adipose tissue-derived stem cells
Figure 4. Effect of age on ASCs quiescence. (A) Representative histogram of TMRM staining in subcutaneous ASCs from young and aged mice. (B, C) Percentage of TMRM lo and TMRM hi ASCs in subcutaneous adipose tissue of young and aged male (B) and female (C) mice. (D, E) Percentage of TMRM lo and TMRM hi ASCs in visceral adipose tissue of young and aged male (D) and female (E) mice. (F) Mean fluorescence intensity of TMRM in young and aged ASCs. (G, H) Percentage of TMRM lo and TMRM hi ASCs in subcutaneous (G) and visceral (H) adipose tissue of mice fed on caloric restricted (CR) and ad-libitum (AL) diet. (n = 3–5 mice per group) P-value < 0.05 = *, ns = non-significant.