Research Paper Volume 16, Issue 10 pp 8511—8523
LncRNA SH3BP5-AS1 promotes hepatocellular carcinoma progression by sponging miR-6838-5p and activation of PTPN4
Figure 2. The impact of SH3BP5-AS1 was diminished by miR-6838-5p. (A) SH3BP5-AS1 expression in HCC cells transfected with pcDNA-SH3BP5-AS1 and miR-6838-5p (or mim-ctrl) was determined by qRT-PCR assay. (B, C) CCK-8 and colony formation assays were used to investigate the effect of the SH3BP5-AS1/miR-6838-5p axis on the proliferation capacity of the HCC cells. (D–F) Wound healing and transwell assays were used to assess the impact of the SH3BP5-AS1/miR-6838-5p axis on the migration and invasion capacity of the HCC cells.