Research Paper Volume 16, Issue 18 pp 12498—12509
SHP2 mediates STAT3/STAT6 signaling pathway in TAM to inhibit proliferation and metastasis of lung adenocarcinoma
Figure 2. Inhibition of SHP2 in TAM can promote the stimulation of STAT3/STAT6 signaling pathway in TAM by lung adenocarcinoma. (A) Co-IP experimental results; (B) Protein band diagram of p-STAT1, p-STAT3, p-STAT5, p-STAT6, IL-4, IL-10; (C) Relative protein expression statistics of p-STAT1, p-STAT3, p-STAT5, p-STAT6, IL-4, IL-10; (D) ELISA detects the concentrations of IL-4 and IL- 10. N=3;**P<0.01;nsP>0.05.