Research Paper Volume 16, Issue 10 pp 8484—8496
Shexiang tongxin dropping pill alleviates myocardial injury induced by coronary microembolization by down-regulating APOC1 to inhibit STAT3 signaling pathway
Figure 2. STDP can attenuate myocardial injury in CME rats and regulate STAT3 signal pathway. Note: (A) H&E staining on myocardial tissues, scale bar of 100 μm; (B, C) Serum levels of cTnI and CK-MB detected by ELISA; (D) qRT-PCR detected the expressions of inflammatory cytokines IL-6, IL-1β and TNF-α in myocardial tissues; (E) Western blot detected the protein expressions of STAT3 signal pathway related proteins. *P < 0.05, ** P < 0.01. STDP, Shexiang Tongxin dropping pill; CME, coronary microembolization. cTnI, troponin; CK-MB, Creatine Kinase Isoenzyme.