Research Paper Volume 16, Issue 10 pp 8484—8496
Shexiang tongxin dropping pill alleviates myocardial injury induced by coronary microembolization by down-regulating APOC1 to inhibit STAT3 signaling pathway
Figure 1. STDP regulates APOC1 expression in the myocardial tissues of CME rat models. Note: (A) Gene expression levels are shown in a heat map, in which each row represents a gene and each column represents a sample of hip joint capsule tissue. The variation in color of red to blue indicates the signal level, with red indicating high signal or upregulation, blue indicating low signal or downregulation. (B) The distribution of differential expressed genes is showed by volcano map. (C) GO analysis on the differential expressed genes. (D) qRT-PCR detected the APOC1 expression in myocardial tissues. (E) Western blot detected the APOC1 protein expression in myocardial tissues. *P < 0.05, ** P < 0.01. Each group had 6 rats and each experiment was repeated for 3 times. STDP, Shexiang Tongxin dropping pill; CME, coronary microembolization.