Research Paper Volume 16, Issue 9 pp 7774—7798

The identification of a N6-methyladenosin-modifed immune pattern to predict immunotherapy response and survival in urothelial carcinoma

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Figure 9. (A) The expression levels of tumors and adjacent normal tissues were evaluated using real-time quantitative PCR. Split-panel box plots contrast the differences in expression levels of various MPIGs between the two types of tissues. (B) Kaplan-Meier analysis and survival curves reveal the disparity in disease-free survival (DFS) among 30 urothelial carcinoma (UC) patients recruited by Shao Yifu Hospital, categorized into high- and low-risk groups based on MPIGs. (C) A heatmap illustrates the infiltration scores of CD8+ T cells, CD4+ T cells, B cells, NK cells, and macrophages in GSE32894 samples, calculated using the ssGSEA method. (D) Box plots compare the differences in infiltration scores of CD8+ T cells, CD4+ T cells, B cells, NK cells, and macrophages between high- and low-risk groups derived from MPIGs.