Research Paper Volume 16, Issue 8 pp 7277—7292
Medium-chain chlorinated paraffins (MCCPs) induce renal cell aging and ferroptosis
Figure 4. MCCPs induced ferroptosis in renal cells. (A) Analysis of the types of renal cell death induced by MCCPs. (B) MCCPs induced iron overload in renal cells. (C) Effects of MCCPs on transferrin, ferroportin, ferritin and NCOA4 expression. (D) Effects of MCCPs on oxidative stress. (E) Effects of MCCPs on lipid peroxidation. (F) Effects of MCCPs on mitochondrial membrane potential. p < 0.05 indicates significant differences.