Identification of biomarkers and immune infiltration characterization of lipid metabolism-associated genes in osteoarthritis based on machine learning algorithms

Yuanye Ma; Yang Liu; Dan Luo; Zhu Guo; Hongfei Xiang; Bohua Chen; Xiaolin Wu

doi:doi:10.18632/aging.205740

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Research Paper Volume 16, Issue 8 pp 7043—7059

Identification of biomarkers and immune infiltration characterization of lipid metabolism-associated genes in osteoarthritis based on machine learning algorithms

Figure 6. Immune cell infiltration analysis of HC and OA based on ssGSEA algorithm. (A) Immune infiltration analysis of 23 type immune cells by ssGSEA. (B) Principal components analysis (PCA) between HC and OA groups. (C–E) Correlation analysis of three diagnostic biomarkers (JUN, NFKB1A and LTC4S) and immune microenvironment.