Identification of a robust biomarker LAPTM4A for glioma based on comprehensive computational biology and experimental verification

Yongqi Ding; Yike Jiang; Hong Zeng; Minqin Zhou; Xuanrui Zhou; Zichuan Yu; Jingying Pan; Xitong Geng; Yanting Zhu; Hao Zheng; Shuhan Huang; Yiyang Gong; Huabin Huang; Chengfeng Xiong; Da Huang

doi:doi:10.18632/aging.205736

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Research Paper Volume 16, Issue 8 pp 6954—6989

Identification of a robust biomarker LAPTM4A for glioma based on comprehensive computational biology and experimental verification

Figure 5. LAPTM4A may affect the invasion and migration through the EMT pathway in glioma. Changes in the expression of n-cadherin, e-cadherin, and MMP 9 after LAPTM4A knockdown (A) with mRNA aspect, (B) with protein aspect. (C, D) Effect of LAPTM4A knockdown on glioma cell invasion and migration.