Research Paper Volume 16, Issue 8 pp 6921—6936
Compound sophora decoction alleviates ulcerative colitis by regulating macrophage polarization through cGAS inhibition: network pharmacology and experimental validation
Figure 3. CSD restores macrophage balance in vitro. (A) iNOS mRNA levels in RAW264.7 cells; (B) Arg1 mRNA levels in RAW264.7 cells; (C) Fluorescence expression of iNOS in RAW264.7 cells, 100X magnification; (D) Fluorescence expression of Arg1 in RAW264.7 cells, 100X magnification; (E) Flow cytometry diagram of M1 and M2 in BMDMs; (F) M2/M1 cell ratio in BMDMs. The data represented as mean ± SD of three independent experiments. Abbreviation: ns: no significance. *p < 0.05, ***p < 0.001 vs. ISD group.