Figure 2. DEGs screening. (A) Volcano plot of IS-related DEGs, where the horizontal coordinate is log2FoldChange, the vertical coordinate is -log10(FDR), red triangles indicate up-regulated DEGs, green triangles indicate down-regulated DEGs and gray nodes indicate genes with no significant differential expression; (B) Heat map of 40 DEGs, where light-red represents disease samples, light-blue represents normal control samples, red represents high gene expression, and blue represents low gene expression. Abbreviations: IS, ischemic stroke; DEGs, differentially expressed genes; FDR, false discovery rate.