Research Paper Volume 16, Issue 7 pp 6478—6487

Stigmasterol alleviates airway inflammation in OVA-induced asthmatic mice via inhibiting the TGF-β1/Smad2 and IL-17A signaling pathways

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Figure 4. Differential activation of the TGF-β1/Smad2 and IL-17A signaling pathway in splenocytes. (A) Flow cytometry results showing expression levels of IL-17A in splenocytes. (B) The plot of IL-17A levels in splenocytes. (C) Differential expression of TGF-β1 gene in splenocytes. (D) Differential expression of IL-17A gene in splenocytes. (E) Differential expression of TGF-β1, p-Smad2, and IL-17A proteins in splenocytes. p < 0.05 indicated statistically significant differences. p < 0.05 indicated statistically significant differences.