Research Paper Volume 16, Issue 7 pp 6478—6487

Figure 2. Effect of stigmasterol on OVA-challenged mice airway inflammation and AHR. (A) Histological H&E staining of airway remodeling, ×200. (B) STG reduced OVA-induced airway hyperresponsiveness. The effects of STG on AHR were detected by an invasive pulmonary facility for small animals (FlexiVent, SCIREQ, USA). Data are expressed as a percentage change from the baseline value. (C) The number of inflammatory cells such as macrophages, lymphocytes, neutrophils, and eosinophils in BALF as detected by flow cytometry. (D) Inflammatory factors in BALF including IL-1β, IL-5, IL-6, IL-13 as determined by ELISA. p < 0.05 indicated statistically significant differences.