Research Paper Volume 16, Issue 8 pp 6773—6795
An LRPPRC-HAPSTR1-PSMD14 interaction regulates tumor progression in ovarian cancer
Figure 5. HAPSTR1 supports tumorigenicity in vivo and regulates the EMT pathway and autophagy markers. (A–C) Tumor weights and volumes in a subcutaneous xenografted nude mice model demonstrated that HAPSTR1 expression promotes ovarian cancer progression in vivo. (D–H) The immunohistochemistry assay suggested that the HAPSTR1 expression level influenced the expression levels of LRPPRC, KI67, and Beclin1 expression. Original magnification, 200x, 400x. *, p < 0.05; **, p < 0.01; ***, p < 0.001.