Research Paper Volume 16, Issue 7 pp 6334—6347

Lactobacillus plantarum 45 activates SHP2 through inhibition of oxidative stress to regulate osteoblast and osteoclast differentiation

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Figure 4. Detection of expressions of relevant proteins in osteoclasts via Western blotting. LP45 inhibits osteoclast formation by modulating histone proteases in macrophages and secreting exosomes to osteoclasts. (A) Detection of expressions of relevant proteins in osteoclasts via Western blotting. (B) Expression levels of relevant proteins in osteoclasts. **p < 0.05, Abbreviation: ns: no statistically significant difference.