Research Paper Volume 16, Issue 7 pp 6290—6313
Identifying an immunogenic cell death-related gene signature contributes to predicting prognosis, immunotherapy efficacy, and tumor microenvironment of lung adenocarcinoma
Figure 4. Construction and validation of the ICD prognostic signature. (A) LASSO Cox regression analysis of ICDGs. (B) Forest plot of the five target genes that compose the ICD signature. (C) Risk score distribution plot showed the distribution of high-risk and low-risk LUAD patients. Scatter plot showed the correlation between the survival status and risk score of LUAD patients. (D) Heatmap for the expression of five crucial genes in low-risk and high-risk subgroups. The survival analysis in TCGA cohort (E) and GSE68465 cohort (F). ROC curves indicated the predictive efficiency of the prognostic signature in TCGA cohort (G) and GSE68465 cohort (H). *p < 0.05, **p < 0.01, ***p < 0.001.