Research Paper Volume 16, Issue 6 pp 5751—5771

Comprehensive analysis of scRNA-seq and bulk RNA-seq reveal the characteristics of disulfidptosis and a prognostic signature in BLCA

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Figure 3. Analysis of DEGs and functional annotation of disulfidptosis. (A) DEGs between gene groups. (B, C) Functional annotation of DRG cluster-related DEGs using GO and KEGG enrichment analysis. (D) Cumulative distribution function curve. (E) Consistency matrix of BLCA sequences with k = 2. (F) Kaplan-Meier curves showed that the disulfidptosis genomic phenotype was significantly associated with OS of BLCA patients. (G) Unsupervised clustering of DEGs to classify patients into different genomic subtypes. (H) Expression of 26 DRGs in gene cluster A and B from the meta cohort. *P < 0.05, **P < 0.01, ***P < 0.001.