Research Paper Volume 16, Issue 7 pp 5987—6007

Figure 3. Identification of two clusters based on hub DEFERGs. (A) The bean plot shows the differential expression of hub DEFERGs between the normal tissues and RPs. (B, C) ROC curve of hub DEFERGs in RPs’ diagnosis. (D, E) The consensus cumulative distribution function (CDF) plot (D) and the relative change in area under the CDF curve (E). (F) The consensus matrix plot is displayed for k = 2 clusters. (G) The PCA plot visually represents the distribution of these two clusters. (H) Boxplots display the expression patterns of hub DEFERGs in cluster 1 and cluster 2. (I) GSVA analysis of biological pathways is conducted between the two distinct clusters, with red indicating activated pathways and blue indicating inhibited pathways.