Identification of key pathways and mRNAs in interstitial cystitis/bladder pain syndrome treatment with quercetin through bioinformatics analysis of mRNA-sequence data

Guang Wang; Pei Li; Si-Wei Su; Rui Xu; Zi-Ye Huang; Tong-Xin Yang; Jiong-Ming Li

doi:doi:10.18632/aging.205682

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Research Paper Volume 16, Issue 7 pp 5949—5966

Identification of key pathways and mRNAs in interstitial cystitis/bladder pain syndrome treatment with quercetin through bioinformatics analysis of mRNA-sequence data

Figure 7. Lpl was involved in the therapeutic process of QCT on IC/BPS in rats. (A) Lpl mRNA expression was detected using RT-qPCR. (B) The IHC staining of bladder tissues. (C) The protein expression of Lpl. (D) The HE staining of bladder tissues. (E, F) Masson staining was used to evaluate the collagen and smooth muscle in bladder tissues. The levels of GAG (G), MPO (H), IL-1β (I), IL-6 (J), TNF-α (K). ^*P < 0.05, ^**P < 0.01, ^***P < 0.001.