Research Paper Volume 16, Issue 7 pp 5949—5966
Identification of key pathways and mRNAs in interstitial cystitis/bladder pain syndrome treatment with quercetin through bioinformatics analysis of mRNA-sequence data
Figure 6. The PPI network and the most significant modules of genes. (A) PPI network was analyzed in B vs. A group and B vs. C group (|log2 Fold change| ≥ 1 and P.adj <0.05) by STRING software. (B) The most significant module was identified by Cytoscape MCODE (degree cutoff = 2, node score cutoff = −0.2, k-core = 2, and max. Depth = 100). (C) The top 10 hub genes were identified by Cytoscape Cytohubba.