Research Paper Volume 16, Issue 6 pp 4980—4999

Figure 6. Effect of the CMS121 diet on plasma metabolites. Differentially expressed metabolites are presented as (A) heat map; (B) volcano plot; (C) table presenting the top ten upregulated or downregulated metabolites, and metabolites related to lipids (D) or amino acids (E). Only sub-pathways with 3 or more differentially expressed metabolites are presented in (D and E), and represent the average ± SD. Abbreviations are: BCAA – branched chain amino acids; Butyrate-X – indicates 4 carbon metabolites related to β-hydroxybutyrate; S/M Acylcarn – small or medium acylcarnitine metabolites; L/Acyl FA – long saturated/monoinsaturated free or acyl fatty acids; L-Poly FA – long polyunsaturated free or acyl-fatty acids. ^*Indicates compounds that have not been confirmed based on a standard, but mass spectral data were appropriate to reveal their identity.