Research Paper Volume 16, Issue 6 pp 5601—5617
WTAP regulates the production of reactive oxygen species, promotes malignant progression, and is closely related to the tumor microenvironment in glioblastoma
Figure 3. WTAP protein is upregulated in GBM tissues. (A) An immunohistochemistry assay was used to analyze the differential expression of WTAP protein in six pairs of GBM tissues and adjacent nontumor tissues. (B) The IHC scores of WTAP in GBM tissues were significantly higher than that of matched adjacent nontumor tissues. (C) Immunohistochemical detection of the WTAP expression levels in paired GBM tissues and adjacent nontumor tissues. (D) The immunofluorescence images of WTAP protein, nucleus, microtubules, and endoplasmic reticulum (ER) in U251 MG cell. *P < 0.05; ***P < 0.001.