Research Paper Volume 16, Issue 6 pp 5567—5580
CRIF1 attenuates doxorubicin-mediated mitochondrial dysfunction and myocardial senescence via regulating PXDN
Figure 3. CRIF1 overexpression inhibited DOX-induced myocardial senescence. (A) The SA-β-gal assay was used to detect myocardial senescence. (B, C) RT-qPCR and western blot detected the expression of p27, p21, and p16. ***P<0.001 vs Control; ###P<0.001 vs DOX+AAV-NC.