Research Paper Volume 16, Issue 6 pp 5224—5248
Development and validation of a novel biomarker panel for Crohn’s disease and rheumatoid arthritis diagnosis and treatment
Figure 2. Identification of common differential genes between CD and RA. (A) Unsupervised clustering PCA plot for CD discovery cohort. (B) Volcano map of differential genes in the CD discovery cohort. (C) Unsupervised clustering heatmap of differential genes in the CD discovery cohort. (D) Unsupervised clustering PCA plot for the RA discovery cohort. (E) Volcano map of differential genes in the RA discovery cohort. (F) Unsupervised clustering heatmap of differential genes in the CD discovery cohort. (G) Venn diagram of co-upregulated differential genes in the CD and RA discovery cohorts. (H) Venn diagram of co-downregulated differential genes in the CD and RA discovery cohorts. Abbreviations: PCA: principal component analysis; CD: Crohn’s disease; RA: rheumatoid arthritis.