Research Paper Volume 16, Issue 6 pp 5207—5223

Allicin treats myocardial infarction in I/R through the promotion of the SHP2 axis to inhibit p-PERK-mediated oxidative stress

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Figure 8. Inhibition of oxidative stress by allicin extract through upregulation of SHP2 expression. (A, B) Allicin extract inhibited the expression of p-PERK, MFN1, NOX2, NOX3, but increased SHP2 expression. Allicin extract did not affect oxidative stress in SHP2-KO rats. **p < 0.01, *p < 0.05, One-way analysis, **p < 0.01, n = 6/group.