Research Paper Volume 16, Issue 6 pp 5207—5223

Allicin treats myocardial infarction in I/R through the promotion of the SHP2 axis to inhibit p-PERK-mediated oxidative stress

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Figure 7. Inhibition of macrophage oxidative stress by allicin extract. (A) Allicin extract had an inhibitory effect on oxidative stress in SHP2-KO rats compared to the model group. Allicin extract had no significant effect on oxidative stress in SHP2-KO rats, indicating that mitochondria are the site of oxidative stress occurrence. (B) Statistical data. One-way analysis, **p < 0.01, n = 6/group.