Research Paper Volume 16, Issue 5 pp 4862—4888

Molecular characteristics and prognostic significances of lysosomal-dependent cell death in kidney renal clear cell carcinoma

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Figure 2. Pan-cancer characteristics of 50 LDCD-RGs. (A, B) Depiction of CNV mutations (gain and loss frequencies) within the cohort of LDCD-RGs manifesting in human tumors. (C) Heatmap was utilized to depict the SNV data of the LDCD-RGs in human tumors. (D) Depiction of mRNA expression magnitudes for LDCD-RGs. (E) Survival landscape assessment was performed on the set of LDCD-RG in human cancers. Genes displaying a P-value exceeding 0.05 are depicted in white, blue represents protective, red represents risk. (F) The methylation landscape governing LDCD-RGs in human tumors. Abbreviations: LDCD-RGs: LDCD-related genes; CNV: Copy Number Variation.