Research Paper Volume 16, Issue 5 pp 4841—4861

HOXC9 characterizes a suppressive tumor immune microenvironment and integration with multiple immune biomarkers predicts response to PD-1 blockade plus chemotherapy in lung adenocarcinoma

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Figure 6. Overexpression of Hoxc9 elicited a promotive role in tumor cells progression. (A) Confirmation of Hoxc9 overexpression in two cell lines with WB. (B, C) Significantly higher cell viabilities were observed in the DDK-Hoxc9 groups of CMT and LCC. (DF) Overexpression of Hoxc9 resulted in a more counts of colony and wider remaining wound (200 μm). (G) Overexpression of Hoxc9 resulted in more invasive counts of cells (100 μm). (*P<0.05, **P<0.01, ***P<0.001).