Figure 4.SORBS1 inhibits MDA-MB-231 and SKBR3 cell invasion and migration. MDA-MB-231 and SKBR3 cells were transfected with SORBS1 overexpression plasmid and siRNA for 48 h. (A) Changes in the migratory ability of MDA-MB-231 and SKBR3 cells were detected by scratch assay. (B) Changes in the invasive ability of MDA-MB-231 and SKBR3 cells were detected by transwell assay (*P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001).