Research Paper Volume 16, Issue 5 pp 4778—4788
The low expression of miR-155 promotes the expression of SHP2 by inhibiting the activation of the ERK1/2 pathway and improves cell pyroptosis induced by I/R in mice
Figure 4. (A) Intersection prediction of downstream genes of miR-155 as SHP2 using TargetScan, mirDIP, and starBase. (B) Binding sites between mRNA and miRNA. (C) Volcano plot of DEGs in GSE24591. (D) Clustering heatmap of DEGs in GSE24591. (E) PPI network. (F) The levels of micRNA-155 expression and SHP2 mRNA were measured.