Research Paper Volume 16, Issue 6 pp 5123—5148

The comprehensive landscape of prognosis, immunity, and function of the GLI family by pan-cancer and single-cell analysis

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Figure 9. Correlation analysis of GLI1, GLI2, and GLI3 with CNV, methylation, and mutation frequency. (A) Type of genetic variation. (B) CNV expression of GLI1, GLI2, and GLI3 in human pan-cancer. (C) Correlation between CNV expression of GLI1, GLI2, and GLI3 and their mRNA expression. (D) Correlation between GLI1, GLI2, and GLI3 and methylation in various tumors. (E) Correlations between GLI1, GLI2, and GLI3 mRNA expression and methylation in various tumors. (F) The mutation frequency of GLI1, GLI2, and GLI3 in various tumors. (G) SNV oncoplot. An oncoplot showing the mutation distribution of GLI1, GLI2, and GLI3 and a classification of SNV types.