Figure 8. Mutation signature mapping of GLI1, GLI2, and GLI3 genes in the cBioPortal database. (A) An overview of the genomic alternations of GLI1, GLI2, and GLI3 occurred in pan-cancer. The mutation frequency and corresponding mutation types of GLI1 (B), GLI2 (C), and GLI3 (D) in different cancers. Mutation sites of GLI1 (E), GLI2 (F), and GLI3 (G). Kaplan-Meier plot showing the comparison of OS (H), DSS (I), and PFS (J) in cases with/without GLI1 gene alterations in the tumor.