Research Paper Volume 16, Issue 5 pp 4591—4608

GBA3 promotes fatty acid oxidation and alleviates non-alcoholic fatty liver by increasing CPT2 transcription

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Figure 6. GBA3 maintains mitochondrial homeostasis by reducing ROS. (A, B) Levels of GSH and GSSG were quantified (**, P < 0.01; ***, P < 0.001). (C) Representative image of ROS detection in cells (Scale bars, 50 μm). (D) ROS was quantified via flow cytometry, P-value was calculated by 2-tailed Student’s t test (*, P < 0.05). (E) Hepatic ROS content was quantitatively determined, P-value was calculated by 2-tailed Student’s t test (**, P < 0.01; ***, P < 0.001).