Research Paper Volume 16, Issue 5 pp 4591—4608

Figure 2. Identification of GBA3 as a hub gene. (A) FAO scores in GSE160016, P-value was calculated by Mann-Whitney U test (*, P < 0.05). (B) Pearson correlation coefficient between the expression of FRDEGs and FAO score (*, P < 0.05). (C) The receiver operating characteristic curves of six statistically significant genes in GSE160016. (D) Relative mRNA expression of six genes in cells and livers. P-value was calculated by 2-tailed Student’s t test (*, P < 0.05; **, P < 0.01; ***, P < 0.001; ns, not significant). (E) Immunoblotting detection of GBA3 in cells. Protein expression was normalized to actin levels and shown as relative values. P-value was calculated by 2-tailed Student’s t test (*, P < 0.05). (F) Immunohistochemical images of GBA3 in livers.