Research Paper Volume 16, Issue 5 pp 4469—4502
Single-cell RNA combined with bulk RNA analysis to explore oxidative stress and energy metabolism factors and found a new prostate cancer oncogene MXRA8
Figure 7. Differential expression and characterization of molecular subtypes in prostate cancer. (A, B) Volcano plots of differentially expressed genes between subtypes, with red indicating upregulation, blue indicating downregulation, and gray indicating no significant difference in gene expression. The labeled genes in the two plots are oxidative stress genes and energy metabolism genes, respectively; (C, D) Bubble plots of KEGG pathway and GOBP functional enrichment analysis results for differentially expressed genes between subtypes; (E, F) Box plots showing differences in enrichment scores for immune-related factor gene sets and immune function gene sets between subtypes.