Research Paper Volume 16, Issue 5 pp 4469—4502
Single-cell RNA combined with bulk RNA analysis to explore oxidative stress and energy metabolism factors and found a new prostate cancer oncogene MXRA8
Figure 5. Dysregulation of oxidative stress and energy metabolism-related genes. (A) Heatmap of significantly differentially expressed oxidative stress genes, with red indicating high expression and blue indicating low expression, and orange and green indicating tumor and normal tissue samples, respectively; (B) Heatmap of significantly differentially expressed energy metabolism-related genes; (C) Box plot showing the expression of commonly differentially expressed oxidative stress and energy metabolism-related genes, with orange and green representing tumor and normal samples, respectively; (D–F) Violin plots showing ssGSEA score differences for oxidative stress-related gene sets in tumor and normal tissues, including oxidative stress response, cellular antioxidant defense, and oxidative stress-induced cell death.