Research Paper Volume 16, Issue 5 pp 4469—4502

Single-cell RNA combined with bulk RNA analysis to explore oxidative stress and energy metabolism factors and found a new prostate cancer oncogene MXRA8

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Figure 3. Identification and functional characterization of oxidative stress-activated populations. (A) AUC scores for specific oxidative stress marker genes; (B) UMAP color-coded plot based on cell activity scores, where brighter colors indicate higher response scores and activity levels to the gene set; (C) Histogram showing the distribution of active and inactive oxidative stress cell populations in different cell groups; (D) Bubble plot of KEGG enrichment results for differentially expressed genes, with bubble size representing the number of enriched genes and color indicating the significance of the enrichment result; (E) Bubble plot of GOBP enrichment results for differentially expressed genes.